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Article

Identification of BIRC6 as a novel intervention target for neuroblastoma therapy.

BMC cancer - 12 Jul 2012

Lamers Fieke, Schild Linda, Koster Jan, Speleman Frank, Øra Ingrid, Westerhout Ellen M, van Sluis Peter, Versteeg Rogier, Caron Huib N, Molenaar Jan J

Abstract excerpt

BACKGROUND: Neuroblastoma are pediatric tumors of the sympathetic nervous system with a poor prognosis. Apoptosis is often deregulated in cancer cells, but only a few defects in apoptotic routes have been identified in neuroblastoma. METHODS: Here we investigated genomic aberrations affecting genes of the intrinsic apoptotic pathway in neuroblastoma. We analyzed DNA profiling data (CGH and SNP arrays) and mRNA...

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Identifiers

PMID: 22788920
DOI: 10.1186/1471-2407-12-285
PMCID: PMC3495678

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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