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Article

Human neuroglobin functions as an oxidative stress-responsive sensor for neuroprotection.

The Journal of biological chemistry - 31 Aug 2012

Watanabe Seiji, Takahashi Nozomu, Uchida Hiroyuki, Wakasugi Keisuke

Abstract excerpt

Mammalian neuroglobin (Ngb) protects neuronal cells under conditions of oxidative stress. The mechanism underlying this function is only partly understood. Here, we report that human Ngb exists in lipid rafts only during oxidative stress and that lipid rafts are crucial for neuroprotection by Ngb...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22787149
DOI: 10.1074/jbc.M112.373381
PMCID: PMC3436268

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22787149-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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