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Article

Sialin (SLC17A5) functions as a nitrate transporter in the plasma membrane.

Proceedings of the National Academy of Sciences of the United States of America - 14 Aug 2012

Qin Lizheng, Liu Xibao, Sun Qifei, Fan Zhipeng, Xia Dengsheng, Ding Gang, Ong Hwei Ling, Adams David, Gahl William A, Zheng Changyu, Qi Senrong, Jin Luyuan, Zhang Chunmei, Gu Liankun, He Junqi, Deng Dajun, Ambudkar Indu S, Wang Songlin

Abstract excerpt

In vivo recycling of nitrate (NO(3)(-)) and nitrite (NO(2)(-)) is an important alternative pathway for the generation of nitric oxide (NO) and maintenance of systemic nitrate-nitrite-NO balance. More than 25% of the circulating NO(3)(-) is actively removed and secreted by salivary glands. Oral co...

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Identifiers

PMID: 22778404
DOI: 10.1073/pnas.1116633109
PMCID: PMC3421170

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22778404-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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