Article
A vesicular transporter that mediates aspartate and glutamate neurotransmission.
Biological & pharmaceutical bulletin - 1 Jan 2010
Miyaji Takaaki, Omote Hiroshi, Moriyama Yoshinori
Abstract excerpt
Aspartate, an excitatory amino acid, is known to be stored in synaptic vesicles and exocytosed from some neurons to perform aspartergic neurotransmission. Through in vitro reconstitution, we found that sialin, a lysosomal sialic acid exporter, is responsible for the vesicular storage of aspartate...
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