Pathogenesis of Septic Shock: Implications for Prevention and Treatment

Abstract excerpt

The innate immune system is in the vanguard of host defenses against infection. Recognition of invasive microbial pathogens is mediated by pattern recognition receptors on the surface of immune cells that recognize pathogen-associated molecular motifs. Considerable progress has been made in recent years in understanding how bacterial products initiate sepsis. In gram-negative sepsis, the LPS-binding protein...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Immune Response and Inflammation
• Share to Neutrophil, Myeloperoxidase and Oxidative Mechanisms
• Share to Sepsis Diagnosis and Treatment