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Methylenetetrahydrofolate reductase polymorphisms C677T and risk of autism in the Chinese Han population.

Genetic testing and molecular biomarkers - 1 Aug 2012

Guo Tianyou, Chen Hong, Liu Bing, Ji Weidong, Yang Chuang

Abstract excerpt

Causes of autism are still unknown. Some studies have shown that autism might be associated with metabolic abnormalities in the folate/homocysteine pathway, which is involved in DNA methylation, thus altering gene expression. The association between the methylenetetrahydrofolate reductase (MTHFR) gene C677T polymorphisms and the risk of autism is still controversial and ambiguous. The purpose of this study was to...

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Source

Identifiers

PMID: 22775456
DOI: 10.1089/gtmb.2012.0091

Genes

MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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