Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Insight into mammalian mitochondrial DNA segregation.

Annals of medicine - 1 Mar 2013

Jokinen Riikka, Battersby Brendan J

Abstract excerpt

Mitochondrial DNA (mtDNA) is essential for aerobic energy production in eukaryotic cells, and mutations in this genome can lead to mitochondrial dysfunction. Human mtDNA mutations are typically heteroplasmic, a mix of mutant and wild-type genomes, which can present as a heterogeneous group of disorders ranging in severity from mild to fatal, and commonly affecting highly aerobic tissues such as heart, skeletal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosome Segregation
Share to DNA, Mitochondrial
Share to Mitochondria

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mutation

Source

Identifiers

PMID: 22775146
DOI: 10.3109/07853890.2012.693190

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Insight into mammalian mitochondrial DNA segregation.PMID 22775146Read ↗

Mammalian mitochondrial genetics: heredity, heteroplasmy and disease.Semantic proximity Read ↗

Mitochondrial DNA mutations and human disease.Semantic proximity Read ↗

Mitochondrial DNA: impacting central and peripheral nervous systems.Semantic proximity Read ↗

Mitochondrial DNA and disease.Semantic proximity Read ↗

The pathophysiology of mitochondrial biogenesis: towards four decades of mitochondrial DNA research.Semantic proximity Read ↗

Mitochondrial DNA mutations: an overview of clinical and molecular aspects.Semantic proximity Read ↗

Mitochondria: Biogenesis and mitophagy balance in segregation and clonal expansion of mitochondrial DNA mutations.Semantic proximity Read ↗

Endangered species: mitochondrial DNA loss as a mechanism of human disease.Semantic proximity Read ↗

Human mitochondrial DNA: roles of inherited and somatic mutations.Semantic proximity Read ↗

Physiology and pathophysiology of mitochondrial DNA.Semantic proximity Read ↗

Molecular genetic aspects of human mitochondrial disorders.Semantic proximity Read ↗

Unsolved issues related to human mitochondrial diseases.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.