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Article

A mouse model of galactose-1-phosphate uridyl transferase deficiency.

Biochemical and molecular medicine - 1 Oct 1996

Leslie N D, Yager K L, McNamara P D, Segal S

Abstract excerpt

Galactose-1-phosphate uridyl transferase (GALT) deficiency causes classical galactosemia in humans. Mice deficient in this enzyme were created by gene targeting. GALT-deficient mice develop biochemical features similar to those seen in humans with GALT deficiency, but fail to develop the pattern of acute toxicity seen in newborns with classical galactosemia. This study suggests that alternative routes of...

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Source

Identifiers

PMID: 8902187
DOI: 10.1006/bmme.1996.0057

Genes

GALT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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