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Article

A mouse model of galactose-1-phosphate uridyl transferase deficiency.

Biochemical and molecular medicine - 1 Oct 1996

Leslie N D, Yager K L, McNamara P D, Segal S

Abstract excerpt

Galactose-1-phosphate uridyl transferase (GALT) deficiency causes classical galactosemia in humans. Mice deficient in this enzyme were created by gene targeting. GALT-deficient mice develop biochemical features similar to those seen in humans with GALT deficiency, but fail to develop the pattern...

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Source

Identifiers

PMID: 8902187
DOI: 10.1006/bmme.1996.0057

Genes

GALT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-8902187-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Experimental galactose-1 phosphate uridylyltransferase (GALT) mRNA therapy improves motor-related phenotypes in a mouse model of Classic GalactosemiaSemantic proximity Read ↗

Acute and long-term outcomes in a Drosophila melanogaster model of classic galactosemia occur independently of galactose-1-phosphate accumulation.Semantic proximity Read ↗

Functional analysis of the mouse galactose-1-phosphate uridyl transferase (GALT)promoter.Semantic proximity Read ↗

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