Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Visualization of hepatic uptake transporter function in healthy subjects by using gadoxetic acid-enhanced MR imaging.

Radiology - 1 Sept 2012

Nassif Ali, Jia Jia, Keiser Markus, Oswald Stefan, Modess Christiane, Nagel Stefan, Weitschies Werner, Hosten Norbert, Siegmund Werner, Kühn Jens-Peter

Abstract excerpt

PURPOSE: To determine if genetic polymorphisms of liver-specific human organic anion transporting polypeptide (OATP) 1B1 and OATP1B3 influence cellular uptake of gadoxetic acid in vitro and if functionally relevant polymorphisms are confounders for liver enhancement by gadoxetic acid in healthy s...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Area Under Curve
Share to Chromatography, Liquid
Share to Contrast Media

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Liver-Specific Organic Anion Transporter 1

Share to Organic Anion Transporters

Share to Organic Anion Transporters, Sodium-Independent

Share to Solute Carrier Organic Anion Transporter Family Member 1B3

Share to Tandem Mass Spectrometry

Source

Identifiers

PMID: 22771883
DOI: 10.1148/radiol.12112061

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22771883-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Visualization of hepatic uptake transporter function in healthy subjects by using gadoxetic acid-enhanced MR imaging.PMID 22771883Read ↗

Unusual Distribution Kinetics of Gadoxetate in Healthy Human Subjects Genotyped for OATP1B1: Application of Population Analysis and a Minimal Physiological-Based Pharmacokinetic Model.Semantic proximity Read ↗

Fluorescence-based methods for studying activity and drug-drug interactions of hepatic solute carrier and ATP binding cassette proteins involved in ADME-ToxSemantic proximity Read ↗

MRI-based cell tracking of OATP-expressing cell transplants by pre-labeling with Gd-EOB-DTPASemantic proximity Read ↗

DCE-MRI detects OATP-expressing transplanted cells using clinical doses of gadolinium contrast agentSemantic proximity Read ↗

Structure/functional aspects of the human riboflavin transporter-3 (SLC52A3): role of the predicted glycosylation and substrate-interacting sites.Semantic proximity Read ↗

Construction of HEK293 cells stably expressing wild-type organic anion transporting polypeptide 1B1 (OATP1B1*1a) and variant OATP1B1*1b and OATP1B1*15.Semantic proximity Read ↗

Hepatic technetium Tc 99m-labeled sestamibi elimination rate and ABCB1 (MDR1) genotype as indicators of ABCB1 (P-glycoprotein) activity in patients with cancer.Semantic proximity Read ↗

OATP1B1/1B3 activity in plated primary human hepatocytes over time in culture.Semantic proximity Read ↗

Feasibility of the functional expression of the human organic anion transporting polypeptide 1B1 (OATP1B1) and its genetic variant 521T/C in the mouse liver.Semantic proximity Read ↗

A human photoacoustic imaging reporter gene using the clinical dye indocyanine greenSemantic proximity Read ↗

Fentanyl pharmacokinetics is not dependent on hepatic uptake by organic anion-transporting polypeptide 1B1 in human beings.Semantic proximity Read ↗

Relationship of hepatic functional imaging to irinotecan pharmacokinetics and genetic parameters of drug elimination.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.