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Article

Feasibility of the functional expression of the human organic anion transporting polypeptide 1B1 (OATP1B1) and its genetic variant 521T/C in the mouse liver.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences - 1 Jan 2017

Chae Yoon-Jee, Lee Kyeong-Ryoon, Lee Jong-Hwa, Lee Wooin, Kim Dae-Duk, Chung Suk-Jae, Maeng Han-Joo

Abstract excerpt

The objective of this study was to examine the feasibility of functional expression of the human organic anion transporting polypeptide 1B1 (hOATP1B1) forms in the liver of the mouse. After the mouse received the gene of interest (i.e., luciferase as the reporter or hOATP1B1) via hydrodynamic gene delivery (HGD) method, the expression was found to be liver-specific while alterations in the serum biochemistry and...

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PMID: 27619346
DOI: 10.1016/j.ejps.2016.09.012

Genes

HGD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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