Null association of NQO1 609C>T and NQO2 -3423G>A polymorphisms with susceptibility and prognosis of Esophageal cancer in north Indian population and meta-analysis.

doi:10.1016/j.canep.2012.06.004

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Article

Null association of NQO1 609C>T and NQO2 -3423G>A polymorphisms with susceptibility and prognosis of Esophageal cancer in north Indian population and meta-analysis.

Cancer epidemiology - 1 Dec 2012

Umar Meenakshi, Upadhyay Rohit, Kumar Shaleen, Ghoshal Uday Chand, Mittal Balraj

Abstract excerpt

INTRODUCTION: NAD(P)H:quinone oxidoreductase 1 (NQO1) and NRH:quinone oxidoreductase 2 (NQO2), involved in detoxification of environmental carcinogens and activation of chemotherapeutic agents, are supposed to play critical role in carcinogenesis. So, we aimed to investigate the association of NQ...

Topics

Adult
Aged
Aged, 80 and over
Case-Control Studies
Esophageal Neoplasms
Genetic Predisposition to Disease
Genotype
Humans
India
Middle Aged
NAD(P)H Dehydrogenase (Quinone)
Polymorphism, Single Nucleotide
Prognosis
Quinone Reductases
Risk Factors
Survival Analysis

Source

Open in PubMed

Identifiers

PMID: 22770696
DOI: 10.1016/j.canep.2012.06.004

Genes

NQO1
NQO2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-22770696-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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