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Article

Platelet activating factor levels and metabolism in Tangier disease: a case study.

Lipids in health and disease - 8 Jul 2012

Kolovou Vana, Papakonstantinou Vasiliki D, Stamatakis George, Verouti Sophia N, Xanthopoulou Marianna N, Kolovou Genovefa, Demopoulos Constantinos A

Abstract excerpt

BACKGROUND: Tangier disease (TD) is a phenotypic expression of rare familial syndrome with mutations in the ABCA1 transporter. The risk of coronary artery disease in patients with TD is variable. On the other hand the pivotal role of Platelet-Activating Factor (PAF) mediator in atheromatosis was found. Plasma lipoproteins are transporters of the PAF acetylhydrolase (PAF-AH) in cells and known as...

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Source

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Identifiers

PMID: 22769014
DOI: 10.1186/1476-511X-11-89
PMCID: PMC3499335

Genes

ABCA1
CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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