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Article

Permanent neonatal diabetes mellitus: same mutation, different glycemic control with sulfonylurea therapy on long-term follow-up.

Journal of clinical research in pediatric endocrinology - 1 Jun 2012

Aydin Banu Kücükemre, Bundak Rüveyde, Baş Firdevs, Maraş Hülya, Saka Nurçin, Günöz Hülya, Darendeliler Feyza

Abstract excerpt

Permanent neonatal diabetes mellitus (PNDM) is a rare condition presenting before six months of age. Mutations in the genes encoding the ATP-sensitive potassium (KATP) channel are the most common causes. Sulfonylurea (SU) therapy leads to dramatic improvement in diabetes control and quality of life in most patients who carry these mutations. Here, we report the long-term follow-up results of two siblings with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Potassium Channels, Inwardly Rectifying

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Source

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Identifiers

PMID: 22672870
DOI: 10.4274/jcrpe.524
PMCID: PMC3386770

Genes

ABCC8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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