Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Directing Differentiation of Human Embryonic Stem Cells Toward Anterior Neural Ectoderm Using Small Molecules

3 Jul 2012

Abstract excerpt

Based on knowledge of early embryo development, where anterior neural ectoderm (ANE) development is regulated by native inhibitors of bone morphogenic protein (BMP) and Nodal/Activin signaling, most published protocols of human embryonic stem cell differentiation to ANE have demonstrated a crucial role for Smad signaling in neural induction. The drawbacks of such protocols include the use of an embryoid body...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CRISPR and Genetic Engineering
Share to Pluripotent Stem Cells Research
Share to Tissue Engineering and Regenerative Medicine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22761025
DOI: 10.1002/stem.1166

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Directing Differentiation of Human Embryonic Stem Cells Toward Anterior Neural Ectoderm Using Small MoleculesPMID 22761025Read ↗

Generation of pancreatic progenitors from human pluripotent stem cells by small moleculesSemantic proximity Read ↗

Efficiently generate functional hepatic cells from human pluripotent stem cells by complete small-molecule strategySemantic proximity Read ↗

Early Cell Fate Decisions of Human Embryonic Stem Cells and Mouse Epiblast Stem Cells Are Controlled by the Same Signalling PathwaysSemantic proximity Read ↗

Small Molecules Greatly Improve Conversion of Human-Induced Pluripotent Stem Cells to the Neuronal LineageSemantic proximity Read ↗

Small Molecule Mesengenic Induction of Human Induced Pluripotent Stem Cells to Generate Mesenchymal Stem/Stromal CellsSemantic proximity Read ↗

Robust and reproducible neuronal differentiation of human embryonic stem cells for neurotoxicologySemantic proximity Read ↗

Efficient Derivation of Human Cardiac Precursors and Cardiomyocytes from Pluripotent Human Embryonic Stem Cells with Small Molecule InductionSemantic proximity Read ↗

A high-content small molecule screen identifies novel inducers of definitive endodermSemantic proximity Read ↗

Differentiation of Human Embryonic Stem Cells to Neural Lineages in Adherent Culture by Blocking Bone Morphogenetic Protein SignalingSemantic proximity Read ↗

Programming Pluripotent Precursor Cells Derived from Xenopus Embryos to Generate Specific Tissues and OrgansSemantic proximity Read ↗

Single Cell Transcriptomics-Informed Induced Pluripotent Stem Cells Differentiation to Tenogenic LineageSemantic proximity Read ↗

Generation of disease-relevant neurons from human pluripotent stem cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.