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Article

Structure of the regulatory domain of the LysR family regulator NMB2055 (MetR-like protein) from Neisseria meningitidis.

Acta crystallographica. Section F, Structural biology and crystallization communications - 1 Jul 2012

Sainsbury Sarah, Ren Jingshan, Saunders Nigel J, Stuart David I, Owens Raymond J

Abstract excerpt

The crystal structure of the regulatory domain of NMB2055, a putative MetR regulator from Neisseria meningitidis, is reported at 2.5 Å resolution. The structure revealed that there is a disulfide bond inside the predicted effector-binding pocket of the regulatory domain. Mutation of the cysteines (Cys103 and Cys106) that form the disulfide bond to serines resulted in significant changes to the structure of the...

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Identifiers

PMID: 22750853
DOI: 10.1107/S1744309112010603
PMCID: PMC3388910

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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