Article
Amadori-glycated phosphatidylethanolamine up-regulates telomerase activity in PANC-1 human pancreatic carcinoma cells.
FEBS letters - 30 Jul 2012
Eitsuka Takahiro, Nakagawa Kiyotaka, Ono Yuichi, Tatewaki Naoto, Nishida Hiroshi, Kurata Tadao, Shoji Naoki, Miyazawa Teruo
Abstract excerpt
Several lines of experimental data have highlighted a key role of Amadori-glycated phosphatidylethanolamine (Amadori-PE) in the development of diabetic complications. Recent epidemiological studies suggest that diabetes mellitus could be a risk factor for some cancers. A characteristic of cancer cells is their immortal phenotype, and the enzyme telomerase contributes to the infinite replicative potential of...
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