Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Disruption of Contactin 4 in two subjects with autism in Chinese population.

Gene - 1 Sept 2012

Guo Hui, Xun Guanglei, Peng Yu, Xiang Xinying, Xiong Zhimin, Zhang Lusi, He Yiqun, Xu Xiaojuan, Liu Yalan, Lu Lina, Long Zhigao, Pan Qian, Hu Zhengmao, Zhao Jingping, Xia Kun

Abstract excerpt

Autism is a heterogeneous childhood neurodevelopmental disorder that is characterised by deficits in verbal communication, impaired social interactions, restricted interests and repetitive behaviours. Using an Illumina HumanCNV370-Quad BeadChip, we identified two Han Chinese individuals with autism and large duplications (~1.6 Mb and ~2.4 Mb) disrupting the same CNTN4 gene. CNTN4 encodes a protein that functions...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asian People
Share to Autistic Disorder

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 3

Share to Gene Duplication

Share to Genetic Predisposition to Disease

Share to Severity of Illness Index

Source

Identifiers

PMID: 22750301
DOI: 10.1016/j.gene.2012.06.051

Genes

CNTN4
CNTN6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Disruption of Contactin 4 in two subjects with autism in Chinese population.PMID 22750301Read ↗

Contactin 4 as an autism susceptibility locus.Semantic proximity Read ↗

Molecular cytogenetic analysis and resequencing of contactin associated protein-like 2 in autism spectrum disorders.Semantic proximity Read ↗

A common genetic variant in the neurexin superfamily member CNTNAP2 increases familial risk of autism.Semantic proximity Read ↗

Mutation analysis of the NRXN1 gene in a Chinese autism cohort.Semantic proximity Read ↗

Linkage, association, and gene-expression analyses identify CNTNAP2 as an autism-susceptibility gene.Semantic proximity Read ↗

Variations analysis of NLGN3 and NLGN4X gene in Chinese autism patients.Semantic proximity Read ↗

Copy-Number Variants in The Contactin-5 Gene Are a Potential Risk Factor for Autism Spectrum DisorderSemantic proximity Read ↗

Contact in the genetics of autism and schizophrenia.Semantic proximity Read ↗

The association of CNTNAP2 rs7794745 gene polymorphism and autism in Iranian population.Semantic proximity Read ↗

Novel de novo 2q14.3 deletion disrupting CNTNAP5 in a girl with intellectual impairment, thin corpus callosum, and microcephaly.Semantic proximity Read ↗

The Human Contactin-Associated Protein-like 2 Gene (CNTNAP2) Spans over 2 Mb of DNA at Chromosome 7q35Semantic proximity Read ↗

Characterization of a family with rare deletions in CNTNAP5 and DOCK4 suggests novel risk loci for autism and dyslexia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.