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Article

Mutation analysis of the NRXN1 gene in a Chinese autism cohort.

Journal of psychiatric research - 1 May 2012

Liu Yalan, Hu Zhengmao, Xun Guanglei, Peng Yu, Lu Lina, Xu Xiaojuan, Xiong Zhimin, Xia Lu, Liu Deyuan, Li Wei, Zhao Jingping, Xia Kun

Abstract excerpt

Autism is a brain developmental disorder characterized by impaired social interaction and communication, as well as restricted and repetitive behaviors. The neurexin-1(NRXN1) gene mapped on chromosome 2p16.3 encodes neurexin, a cell adhesion molecule and receptor in the vertebrate nervous system. Rare de novo alterations and copy number variations (CNVs) suggested neurexin-1 as a candidate gene for the...

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Source

Identifiers

PMID: 22405623
DOI: 10.1016/j.jpsychires.2011.10.015

Genes

NRXN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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