Article
[Analysis of a program for atypical familial microcytosis. Molecular basis of alpha-thalassemia].
Sangre - 1 Aug 1990
Villegas Martínez A
Abstract excerpt
The results of a programme for the study of atypical familial microcytosis are analysed in this paper. The techniques used were "in vitro" synthesis of globin chains in tritiated leucine-labelled reticulocytes and genetic mapping with different restriction enzymes, plus the usual hematologic values. Of the 134 syntheses performed, 73 showed alpha/beta ratio lower than 1 (alpha-thalassaemia). The lowest values,...
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