Article
[Globin gene mutation is a model of genetic abnormalities].
Rinsho byori. The Japanese journal of clinical pathology - 1 Mar 1999
Hattori Y
Abstract excerpt
Hemoglobin has been extensively studied as a prototype of molecular abnormality, and abnormal hemoglobins have disclosed a number of molecular pathogeneses. Genetic analysis of hemoglobin has also contributed to recent advances in molecular biology. Here, thalassemia (thal) is examined. It is a congenital type of hemolytic anemia caused by defective production of either alpha- or beta-globin due to various...
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