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Article

AdapterRemoval: easy cleaning of next-generation sequencing reads.

BMC research notes - 2 Jul 2012

Lindgreen Stinus

Abstract excerpt

BACKGROUND: With the advent of next-generation sequencing there is an increased demand for tools to pre-process and handle the vast amounts of data generated. One recurring problem is adapter contamination in the reads, i.e. the partial or complete sequencing of adapter sequences. These adapter sequences have to be removed as they can hinder correct mapping of the reads and influence SNP calling and other...

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PMID: 22748135
DOI: 10.1186/1756-0500-5-337
PMCID: PMC3532080

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