Article
Heterologous interactions between NS1 proteins from different influenza A virus subtypes/strains.
Science China. Life sciences - 1 Jun 2012
Li Weizhong, Zhang Heng, Wang Gefei, Zhang Chi, Zeng Xiangxing, Liu Hui, Chen Xiaoxuan, Xu Yanxuan, Li Kangsheng
Abstract excerpt
Non-structural protein 1 (NS1) of the influenza virus plays a crucial role in modulating the host immune response and facilitating virus replication. The formation of a homodimer or an oligomer is necessary for NS1 to exert its function efficiently. In the present study, the NS1 protein from the A/Shantou/602/06(H3N2) virus (herein abbreviated as NS32) was found to interact with NS1 from A/Shantou/169/06(H1N1),...
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