Article
[A study of interleukin-10 gene polymorphism in irritable bowel syndrome].
Zhonghua nei ke za zhi - 1 Apr 2006
Wang Bang-mao, Jiang Xiao-zhong, Yang Yu-long, Liu Wen-tian, Cao Xiao-cang, Zhao Xiao-zhi
Abstract excerpt
OBJECTIVE: To investigate whether three diallelic polymorphisms at the position -1082, -819 and -592 in the promoter region of the IL-10 gene were associated with diarrhea-predominant irritable bowel syndrome (D-IBS). METHODS: The IL-10 gene -1082, -819 and -592 position polymorphisms were genotyped by amplification refractory mutation systems-polymerase chain reaction (ARMS-PCR) methods in 43 patients with D-IBS...
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