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Article

Norovirus P Particle: A Subviral Nanoparticle for Vaccine Development Against Norovirus, Rotavirus and Influenza Virus

1 Jun 2012

Abstract excerpt

Noroviruses (NoVs) are important pathogens causing epidemic acute gastroenteritis that affects millions of people worldwide. The protruding (P) domain of the NoV capsid protein, the surface antigen of NoV, forms a 24-mer subviral particle called the P particle that is an excellent candidate vaccine against NoVs. The P particles are easily produced in Escherichia coli, highly stable and highly immunogenic. Each P...

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PMID: 22734641
DOI: 10.2217/nnm.12.62

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