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Article

Norwalk virus-like particles as vaccines

1 Mar 2010

Abstract excerpt

Noroviruses (NoV) cause the great majority of epidemic nonbacterial gastroenteritis in humans. Expression of the capsid protein in recombinant systems, including insect and plant cells, yields assembly of virus-like particles (VLPs) that mimic the antigenic structure of authentic virions, and are relatively acid- and heat-stable. Norwalk virus (NV), the prototype NoV, has been studied extensively, and Norwalk...

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PMID: 20218858
DOI: 10.1586/erv.09.163

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