Article
Dynamical systems approach to endothelial heterogeneity.
Circulation research - 22 Jun 2012
Regan Erzsébet Ravasz, Aird William C
Abstract excerpt
Endothelial cells display remarkable phenotypic heterogeneity. An important goal is to elucidate the scope and mechanisms of endothelial heterogeneity and to use this information to develop vascular bed-specific therapies. We reexamine our current understanding of the molecular basis of endothelial heterogeneity. We introduce multistability as a new explanatory framework in vascular biology. We draw on the field...
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