Article
PTPN22 polymorphism presumably plays a role in the genetic background of chronic spontaneous autoreactive urticaria.
Dermatology (Basel, Switzerland) - 1 Jan 2012
Brzoza Z, Grzeszczak W, Rogala B, Trautsolt W, Moczulski D
Abstract excerpt
BACKGROUND: The association of chronic urticaria (CU) with autoimmune disorders is relatively well proved. Protein tyrosine phosphatase-22 (PTPN22) is considered to be one of the strongest genetic factors for human autoimmunity. We decided to evaluate whether additional, non 1858C>T, PTPN22 variants are independent contributors to the risk of CU occurrence in the Polish population. METHODS: A total of 91 CU...
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