Article
Lack of association of programmed cell death 1 gene (PDCD1) polymorphisms with susceptibility to chronic urticaria in patients with positive autologous serum skin test.
Journal of investigational allergology & clinical immunology - 1 Jan 2012
Brzoza Z, Grzeszczak W, Trautsolt W, Moczulski D
Abstract excerpt
BACKGROUND: Autoimmune mechanisms play an important role in the pathophysiology of chronic urticaria (CU), and the autologous serum skin test (ASST) helps to identify patients with autoreactive CU. One of the factors involved in autoreactive mechanisms is the cell surface receptor programmed death-1 which is encoded by the programmed cell death 1 gene (PDCD1). OBJECTIVE: To investigate whether PDCD1 polymorphisms...
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