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Article

Aberrant expression of splicing factors in newly diagnosed acute myeloid leukemia.

Onkologie - 1 Jan 2012

Liu Jing, Huang Bo, Xiao Yun, Xiong Huo-Mei, Li Jing, Feng Dan-Qin, Chen Xi-Min, Zhang Hai-Bin, Wang Xiao-Zhong

Abstract excerpt

BACKGROUND: Acute myeloid leukemia (AML) is the most common type of blood cancer in adults. Emerging evidence is establishing a connection between AML and aberrant alternative splicing of pre-mRNA, which may result from aberrant expression of splicing factors, the mediators of splicing reactions. MATERIAL AND METHODS: Using quantitative real-time polymerase chain reaction, we measured mRNA expression of 7...

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Topics

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Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Leukemia, Myeloid, Acute

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Source

Identifiers

PMID: 22722453
DOI: 10.1159/000338941

Genes

SRSF1
SRSF3
SRSF4
CASP8
HNRNPA1
SRSF2
SRSF5
SRSF6
SRSF7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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