Article
Identification of a strong genetic background for progressive cardiac conduction defect by epidemiological approach.
Heart (British Cardiac Society) - 1 Sept 2012
Gourraud Jean Baptiste, Kyndt Florence, Fouchard Swanny, Rendu Eric, Jaafar Philippe, Gully Claude, Gacem Karim, Dupuis Jean Marc, Longueville Aurelie, Baron Estelle, Karakachoff Matilde, Cebron Jean Pierre, Chatel Stephanie, Schott Jean Jacques, Le Marec Hervé, Probst Vincent
Abstract excerpt
INTRODUCTION: Progressive cardiac conduction defect (PCCD) is a frequent disease attributed to degeneration and fibrosis of the His bundle. Over the past years, gene defects have been identified demonstrating that PCCD could be a genetic disease. The aim of this study was to show a familial aggregation for PCCD using a genetic epidemiological approach to improve in fine genetic knowledge of the transmission of...
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