Article
Association of -592 region of IL-10 polymorphisms with asthma in south-eastern Iranian patients.
Clinical laboratory - 1 Jan 2012
Hakimizadeh Elham, Arababadi Mohammad Kazemi, Hassanshahi Gholamhossein, Ahmadabadi Behzad Nasiri, Hakimi Hamid, Rezaeian Mohsen, Salehabadi Vajihe Akbarpour, Yousefidaredor Hassan, Abousaidi Hamid, Kennedy Derek
Abstract excerpt
BACKGROUND: Cytokines are considered important factors for the pathogenesis of asthma as they play a key role in the regulation of immune responses. The aim of this study was to investigate the association between this disease and polymorphisms in the -592 region of the IL-10 gene. METHODS: This study was carried out on 100 asthmatic patients and 100 healthy controls. PCR-RFLP was applied to examine the...
Topics
- Adolescent
- Adult
- Aged
- Alleles
- Amplified Fragment Length Polymorphism Analysis
- Asthma
- Case-Control Studies
- Female
- Gene Frequency
- Genetic Predisposition to Disease