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Article

Lineage-specific evolution of T-cell immunoglobulin and mucin domain 1 gene in the primates.

Immunogenetics - 1 Sept 2012

Ohtani Hitoshi, Naruse Taeko K, Iwasaki Yuki, Akari Hirofumi, Ishida Takafumi, Matano Tetsuro, Kimura Akinori

Abstract excerpt

T-cell immunoglobulin domain and mucin domain containing protein 1 (TIM1), also known as a cellular receptor for hepatitis A virus (HAVCR1) or a molecule induced by ischemic injury in the kidney (KIM1), is involved in the regulation of immune responses. We investigated a natural selection history of TIM1 by comparative sequencing analysis in 24 different primates. It was found that TIM1 had become a pseudogene in...

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Source

Identifiers

PMID: 22710823
DOI: 10.1007/s00251-012-0628-y

Genes

HAVCR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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