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Article

Functional and phenotypical impairment of polymorphonuclear cells in atopic dermatitis: an additional cause for the known susceptibility to infections?.

Dermatology (Basel, Switzerland) - 1 Jan 2012

Fierro Maria Teresa, Banche Giuliana, Marenco Federica, Novelli Mauro, Allizond Valeria, Mandras Narcisa, Murabito Pierangela, Merlino Chiara, Quaglino Pietro, Bernengo Maria Grazia, Cuffini Anna Maria

Abstract excerpt

BACKGROUND: Atopic dermatitis (AD) patients present an high susceptibility to infections. The phagocytic activity of polymorphonuclear granulocytes (PMNs) is mediated by the interactions between Toll-like receptors (TLRs) and pathogen-associated molecular patterns. OBJECTIVE: To investigate functional activity and phenotype of PMNs in AD patients. METHODS: In vitro PMN phagocytosis and intracellular killing...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22710427
DOI: 10.1159/000339180

Genes

TLR2
TLR4
TLR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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