Article
Functional and phenotypical alterations of polymorphonuclear cells in Sézary syndrome patients.
European journal of dermatology : EJD - 1 Jan 2000
Fierro Maria Teresa, Cuffini Anna Maria, Novelli Mauro, Banche Giuliana, Allizond Valeria, Comessatti Alessandra, Brizio Matteo, Scalas Daniela, Merlino Chiara, Quaglino Pietro, Bernengo Maria Grazia
Abstract excerpt
Sézary syndrome (SS), the leukemic variant of cutaneous T-cell lymphoma (CTCL), has a poor prognosis and infections represent the most frequent cause of death. Polymorphonucleate granulocytes (PMNs) constitute an essential part of the innate immune system: their phagocytic and killing activity against pathogens is mediated by the interactions between Toll-like receptors (TLRs) and the Pathogen-associated...
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