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Article

Staphylococcus aureus VRSA-11B is a constitutive vancomycin-resistant mutant of vancomycin-dependent VRSA-11A.

Antimicrobial agents and chemotherapy - 1 Sept 2012

Périchon Bruno, Courvalin Patrice

Abstract excerpt

Vancomycin-resistant Staphylococcus aureus VRSA-10 was isolated in 2009, whereas VRSA-11A and VRSA-11B were isolated from the same patient in 2010. Growth curves and determination of the nature of the peptidoglycan precursors and of the VanX d,d-dipeptidase activity in the absence and in the presence of vancomycin indicated that vancomycin resistance was inducible in VRSA-10, that VRSA-11A was partially dependent...

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Identifiers

PMID: 22710116
DOI: 10.1128/AAC.00454-12
PMCID: PMC3421854

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