Article
Homologies between the major histocompatibility complex of man and cattle: consequences for disease resistance and susceptibility.
The veterinary quarterly - 1 Oct 1990
Giphart M J, Groenen M A, van der Poel J J
Abstract excerpt
The major histocompatibility complex (MHC) of mammals contains a large number of mostly duplicated genes. In the HLA system (the MHC of man), which is by far the best-studied major histocompatibility system so far, roughly 20 genes have been defined and mapped. They code for three classes of proteins: HLA-A, -B and -C (Class I), HLA-DP, -DQ and -DR (Class II) and serum complement components C2, C4 and Bf (Class...
Topics
- Animals
- Cattle
- Genetic Predisposition to Disease
- Humans
- Immunity, Innate
- Major Histocompatibility Complex