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Article

SRY-positive 78, XY ovotesticular disorder of sex development in a wolf cloned by nuclear transfer.

Journal of veterinary science - 1 Jun 2012

Kang Jung Taek, Kim Hyung Jin, Oh Hyun Ju, Hong So Gun, Park Jung Eun, Kim Min Jung, Kim Min Kyu, Jang Goo, Kim Dae Yong, Lee Byeong Chun

Abstract excerpt

Recently, we reported the three wolves cloning with normal karyotype from somatic cells of endangered male gray wolves (Canis lupus), but one wolf had female external genitalia. In this study, we conducted further clinical, histological, and genetic analyses. This cloned wolf had a normal uterus but developed ovotestis. Through molecular analysis of the SRY gene, a mutation in the coding sequence of SRY gene...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22705746
DOI: 10.4142/jvs.2012.13.2.211
PMCID: PMC3386349

Genes

SRY

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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