Article
Dual R3R5 tropism characterizes cerebrospinal fluid HIV-1 isolates from individuals with high cerebrospinal fluid viral load.
AIDS (London, England) - 10 Sept 2012
Karlsson Ulf, Antonsson Liselotte, Ljungberg Bengt, Medstrand Patrik, Esbjörnsson Joakim, Jansson Marianne, Gisslen Magnus
Abstract excerpt
OBJECTIVE: To study the use of major and alternative coreceptors by HIV-1 isolates obtained from paired plasma and cerebrospinal fluid (CSF) samples. DESIGN: Paired plasma and CSF isolates from HIV-1-infected individuals with varying clinical, virologic, and immunologic parameters were assessed for the ability to infect indicator cells expressing a panel of coreceptors with documented expression in the central...
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