Article
IL23R(Arg381Gln) functional polymorphism is associated with active pulmonary tuberculosis severity.
Clinical and vaccine immunology : CVI - 1 Aug 2012
Ben-Selma Walid, Boukadida Jalel
Abstract excerpt
The purpose of our study was to investigate the association between a functional single nucleotide polymorphism (SNP) in the interleukin-23 receptor gene (IL23R; rs11209026, 1142 G(wild type) → A(reduced function), Arg381Gln) and disease severity outcome in pulmonary tuberculosis (TB) in the Tunisian population. SNP was investigated in a population of 168 patients with active pulmonary TB (cases were stratified...
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