Article
Biological roles of the Podospora anserina mitochondrial Lon protease and the importance of its N-domain.
PloS one - 1 Jan 2012
Adam Céline, Picard Marguerite, Déquard-Chablat Michelle, Sellem Carole H, Hermann-Le Denmat Sylvie, Contamine Véronique
Abstract excerpt
Mitochondria have their own ATP-dependent proteases that maintain the functional state of the organelle. All multicellular eukaryotes, including filamentous fungi, possess the same set of mitochondrial proteases, unlike in unicellular yeasts, where ClpXP, one of the two matricial proteases, is absent. Despite the presence of ClpXP in the filamentous fungus Podospora anserina, deletion of the gene encoding the...
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