ABCMdb: a database for the comparative analysis of protein mutations in ABC transporters, and a potential framework for a general application.

Abstract excerpt

To overcome the pathological phenomena caused by altered function of ABC (ATP Binding Cassette) proteins, their mechanisms of action are extensively investigated, often involving the design of mutant constructs for experiments. Designing mutagenetic constructs, interpreting the result of mutagenetic experiments, and finding individual genetic variants require an extensive knowledge of previously published...

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