Article
Evaluation of single-nucleotide polymorphisms as internal controls in prenatal diagnosis of fetal blood groups.
Transfusion - 1 Feb 2013
Doescher Andrea, Petershofen Eduard K, Wagner Franz F, Schunter Markus, Müller Thomas H
Abstract excerpt
BACKGROUND: Determination of fetal blood groups in maternal plasma samples critically depends on adequate amplification of fetal DNA. We evaluated the routine inclusion of 52 single-nucleotide polymorphisms (SNPs) as internal reference in our polymerase chain reaction (PCR) settings to obtain a p...
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