Article
The controversy about controls for fetal blood group genotyping by cell-free fetal DNA in maternal plasma.
Current opinion in hematology - 1 Nov 2011
Scheffer Peter G, de Haas Masja, van der Schoot C Ellen
Abstract excerpt
PURPOSE OF REVIEW: Fetal blood group genotyping using cell-free fetal DNA from maternal plasma is routinely performed in alloimmunized women and has been introduced for targeted antenatal anti-D prophylaxis. The necessity to control for extraction of fetal DNA in these tests is questioned by many. This review describes the various types of controls for preventing false-negative results and discusses their value....
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