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Article

Altered expression and signal transduction of endothelin-1 receptors in heritable and idiopathic pulmonary arterial hypertension.

Journal of cellular physiology - 1 Feb 2013

Yu Jun, Taylor Linda, Wilson Jamie, Comhair Suzy, Erzurum Serpil, Polgar Peter

Abstract excerpt

Human pulmonary arterial smooth muscle cells (PASMC) were isolated from elastic pulmonary arteries dissected from lungs of individuals with and without pulmonary arterial hypertension (PAH). Reflecting increased smooth muscle constriction in cells from PAH subject, Ca(2+) influx in response to en...

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Share to Bone Morphogenetic Protein Receptors, Type II
Share to Calcium
Share to Familial Primary Pulmonary Hypertension

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hypertension, Pulmonary

Share to Muscle, Smooth, Vascular

Share to Pulmonary Artery

Share to Receptor, Endothelin A

Share to Receptor, Endothelin B

Source

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Identifiers

PMID: 22688668
DOI: 10.1002/jcp.24132
PMCID: PMC3496420

Genes

PAH
BMPR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22688668-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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