Article
Common immunogenetic profile in children with multiple autoimmune diseases: the signature of HLA-DQ pleiotropic genes.
Autoimmunity - 1 Sept 2012
Larizza Daniela, Calcaterra Valeria, Klersy Catherine, Badulli Carla, Caramagna Claudia, Ricci Antonio, Brambilla Paola, Salvaneschi Laura, Martinetti Miryam
Abstract excerpt
Type 1 diabetes mellitus (T1DM), celiac disease (CD) and autoimmune thyroid disease (ATD) are autoimmune conditions relatively common in paediatric age and frequently occur in association in the same subject. This event is not by chance and requires an explanation. Here, we studied the distribution of HLA-DQ αβ heterodimers in 334 Italian children with T1DM, ATD and CD alone or in association and in 224 Italian...
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