Article
CYP2C19 genotype-guided antiplatelet therapy in a patient with clopidogrel resistance.
Connecticut medicine - 1 May 2012
Rai Mridula, Seip Richard L, Gupta Ankur, McKay Raymond G, Hirst Jeffrey, Thompson Paul D, Ruaño Gualberto
Abstract excerpt
We report a switch in antiplatelet medication based on platelet function and CYP2C19 genotype test results in a 74-year-old man with severe coronary arterial disease. Upon bare metal stent implantation at age 66, clopidogrel therapy (75 mg/ day) was initiated to supplement aspirin. Over the next eight years, the patient required multiple percutaneous coronary interventions for de novo coronary stenosis and...
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