Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MicroRNA93 Regulates Proliferation and Differentiation of Normal and Malignant Breast Stem Cells

7 Jun 2012

Abstract excerpt

MicroRNAs (miRNAs) play important roles in normal cellular differentiation and oncogenesis. microRNA93 (mir-93), a member of the mir106b-25 cluster, located in intron 13 of the MCM7 gene, although frequently overexpressed in human malignancies may also function as a tumor suppressor gene. Using a series of breast cancer cell lines representing different stages of differentiation and mouse xenograft models, we...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Cancer-related molecular mechanisms research
Share to MicroRNA in disease regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22685420
DOI: 10.1371/journal.pgen.1002751

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MicroRNA93 Regulates Proliferation and Differentiation of Normal and Malignant Breast Stem CellsPMID 22685420Read ↗

Epigenetic silencing of microRNA-203 is required for EMT and cancer stem cell propertiesSemantic proximity Read ↗

Comparative Analysis of microRNAs that Stratify in vitro Mammary stem and Progenitor Activity Reveals Functionality of Human miR-92b-3pSemantic proximity Read ↗

MicroRNA100 Inhibits Self-Renewal of Breast Cancer Stem–like Cells and Breast Tumor DevelopmentSemantic proximity Read ↗

Suppression of Breast Cancer Stem Cells and Tumor Growth by the RUNX1 Transcription FactorSemantic proximity Read ↗

A miRNA screen identifies a transcriptional program controlling the fate of adult stem cellSemantic proximity Read ↗

MicroRNA-1 down-regulates proliferation and migration of breast cancer stem cells by inhibiting the Wnt/β-catenin pathway.Semantic proximity Read ↗

Leptin–STAT3–G9a Signaling Promotes Obesity-Mediated Breast Cancer ProgressionSemantic proximity Read ↗

Downregulation of miRNA-200c Links Breast Cancer Stem Cells with Normal Stem CellsSemantic proximity Read ↗

Downregulation of miRNA-200c Links Breast Cancer Stem Cells with Normal Stem CellsSemantic proximity Read ↗

The STAT5-regulated miR-193b locus restrains mammary stem and progenitor cell activity and alveolar differentiationSemantic proximity Read ↗

MiR-93-5p inhibits the EMT of breast cancer cells via targeting MKL-1 and STAT3Semantic proximity Read ↗

Integrin αvβ3 Drives Slug Activation and Stemness in the Pregnant and Neoplastic Mammary GlandSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.