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Longevity and the long arm of epigenetics: acquired parental marks influence lifespan across several generations.

BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Aug 2012

Pang Shanshan, Curran Sean P

Abstract excerpt

A recent study reported that longevity in Caenorhabditits elegans can be inherited over several generations. This is probably achieved through the following epigenetic mechanism: inherited demethylated histones at some central loci, such as miRNA, transcription factors or signaling regulators affect the expression of certain genes leading to the longevity phenotype.

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Identifiers

PMID: 22674543
DOI: 10.1002/bies.201200046
PMCID: PMC3779125

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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