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Article

Promises and Challenges of MicroRNA-based Treatment of Multiple Myeloma

1 Aug 2012

Abstract excerpt

MicroRNAs (miRNAs) recently emerged with a key role in multiple myeloma (MM) pathophysiology and are considered important regulators of MM cell growth and survival. Since miRNAs can act either as oncogenes or tumour suppressors, the potential of targeting the miRNA network arises as a novel therapeutic approach for human cancer. Potential strategies based on miRNA therapeutics basically rely on miRNA inhibition...

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PMID: 22671926
DOI: 10.2174/156800912802429355

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