Article
Negative HCV-RNA 2 weeks after initiation of treatment predicts sustained virological response to pegylated interferon alfa-2a and ribavirin in patients with chronic hepatitis C.
Scandinavian journal of gastroenterology - 1 Sept 2012
Christensen Peer Brehm, Krarup Henrik Bygum, Laursen Alex Lund, Madsen Poul Henning, Pedersen Court, Schlichting Poul, Orholm Marianne, Ring-Larsen Helmer, Bukh Jens, Krogsgaard Kim
Abstract excerpt
OBJECTIVE: The aim of this study was to examine the early viral kinetics as predictor for sustained virological response (SVR) during hepatitis C treatment. MATERIALS AND METHODS: We included patients with biopsy-proven chronic hepatitis C and ALT above the upper limit of normal, who received a standard treatment of pegylated interferon alfa-2a and ribavirin. The HCV-RNA concentration (limit of detection 20...
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